Histology Fact Sheet: Male


The average testis in an adult man has between 400 and 600 seminiferous tubules.

Histology slide of testes
Histology slide courtesy of Histology-World!

Sertoli cells produce inhibin and androgen-binding protein. The interstitial cells of Leydig produce testosterone.


The corpora cavernosa and corpus spongiosum are erectile tissue. There are two corpora cavernosa and one corpus spongiosum.

histology of testesAccessory Glands

The male accessory glands contain the bulbourethral glands, seminal vesicles, and prostate.

Bulbourethral Glands

The bulbourethral glands are also called Cowper's glands. The bulbourethral glands are found in males and are homologous to the Bartholin's glands in females.

Seminal Vesicles

Pseudostratified columnar epithelium lines the seminal vesicles.


The prostate is made of compound tuboloalveolar glands.

The glands of the prostate lie in a fibromuscular stroma. It is also referred to as a fibroelastic stroma. There are bundles of smooth muscle within dense irregular connective tissue.

The spherical structures seen in some prostatic alveoli are called prostatic concretions.

Genital Duct System

The male genital duct system contains: rete testes, tubuli recti, ductuli efferentes, ductus epididymidis, and ductus deferens.


Pseudostratified epithelium lines the epididymis. Stereocilia are very long microvilli. Stereocilia are seen in the epididymis (and the hair cells of the ear).

Vas Deferens

There are three layers of smooth muscle in the vas deferens. There is an inner longitudinal, a middle circular, and an outer longitudinal.  Pseudostratified epithelium lines the vas deferens.


Histology: A Text and Atlas
Michael H. Ross/Edward J. Reith