Third trimester placenta chorionic villi stained with anti-corticotropin releasing hormone antibody. corticotropin releasing hormone positive syncytial knots (red arrows) with surrounding negative syncytium (pink arrows).
Histology slide and description courtesy of Harvey J. Kliman, M.D., Ph.D.; Yale University School of Medicine. From abstract: Synctial Knots Are the Source of Placental CRH
Reprinted with permission.